Wu LabExploring the chemical origins and evolution of biological systems.

Research

Our laboratory studies fundamental principles underlying molecular evolution, RNA chemistry, and the emergence of biological information systems.

01

Origin of Translation Systems

02

RNA World and Molecular Evolution

03

Synthetic Biology and Chemical Evolution

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SELECTED PUBLICATIONS

2010 / 2025

Journal of the American Chemical Society, 147(43), 39212–39222 (2025)

Efficient Assembly of Functional RNA by in Situ Phosphate Activation and Loop-Closing Ligation

Jian Zhang, Aleksandar Radakovic, Filip Bošković, Harry R. M. Aitken, Long-Fei Wu*, and Jack W. Szostak*
Efficient Assembly of Functional RNA by in Situ Phosphate Activation and Loop-Closing Ligation graphical abstract
02PUBLICATION / 2026

[JOURNAL PLACEHOLDER] (2026)

[PUBLICATION TITLE PLACEHOLDER]

[AUTHORS PLACEHOLDER]
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Zhangjiang Institute for Advanced Study campus

CONTACT US

E-mail: lfwu@sjtu.edu.cn

Office: Room 403, Building 4, Frontiers Science Center for Transformative Molecules

Address: Shanghai Jiao Tong University - Zhangjiang Institute for Advanced Study, No. 429 Zhangheng Road, Shanghai, China